RYK mAb (ATKll.4) B Cell Engineering Specific Plasmid (CAT#: BGS-1223-CR10)

This product is a B cell engineering plasmid designed by genomic integration of B cell receptors (RFP-MNDU3-Sec/SPI-CD79α-CD8-CBP) and CRISPR-Cas (Cas12a (Cpf1)-ssRNA-NNGRRT-Wap) systems. This product can precisely introduce cassettes of several kb size into the genome of various B cells to enhance surface expression and antigen recognition of a synthetic BCRs.

Datasheet

Specifications

Clone ATKll.4
Host Humanized
Targeting Cell Type Raji
Reporter gene RFP
Promoter MNDU3
Signal peptides Sec/SPI
Signaling domains CD79α
TM domains CD8
Detection tags CBP
Linkers SEG
Co-Receptors LILRB
Vector Type Baculovirus-AAV
Vector Name BGpCDH4
Class 2 single-Cas
Type III
Subtype B
Effector Cas12a (Cpf1)
DNA Type ssRNA
Nuclease domains Unknown
TracrRNA requirement YES
PAM/PFS NNGRRT
Insertion Wap
Construction RFP-MNDU3-CD79α-Cas12a (Cpf1)-ssRNA-Wap

Target Information

Target RYK
Alternative Names RYK; D3S3195; JTK5; JTK5A; RYK1; receptor-like tyrosine kinase; receptor like tyrosine kinase

Product Properties

Format Liquid/lyophilized
Shipping It is usually shipped overnight at room temperature in small cardboard boxes. If hot temperatures are expected during transit, they will be shipped in polystyrene containers with gel ice packs.
Handling Advice No special measures are necessary. Keep away from food, drink and animal feedingstuffs.
Storage Plasmid (lyophilized), short-time storage at Room Temperature, recommended store at -20°C or -80°C ; Plasmid (Liquid), blue ice store at 4°C.
COA

Certificate of Analysis Lookup

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