RYK mAb (ATK5.5) B Cell Engineering Specific Plasmid (CAT#: BGS-1223-CR9)

This product is a B cell engineering plasmid designed by genomic integration of B cell receptors (CAT-MNDU3-Tat/SPI-CD79α-CD28-Myc) and CRISPR-Cas (Cas12c (C2c3)-dsDNA-RuvC-NGG-Csn) systems. This product can precisely introduce cassettes of several kb size into the genome of various B cells to enhance surface expression and antigen recognition of a synthetic BCRs.

Datasheet

Specifications

Clone ATK5.5
Host Humanized
Targeting Cell Type Farage-Luc2
Reporter gene CAT
Promoter MNDU3
Signal peptides Tat/SPI
Signaling domains CD79α
TM domains CD28
Detection tags Myc
Linkers Flexible Linker
Co-Receptors LILRB
Vector Type Adenoviruses
Vector Name BGpCDH3
Class 1 multi-Cas
Type IV
Subtype A, B, C, D, E, F
Effector Cas12c (C2c3)
DNA Type dsDNA
Nuclease domains RuvC
TracrRNA requirement No
PAM/PFS NGG
Insertion Csn
Construction CAT-MNDU3-CD79α-Cas12c (C2c3)-dsDNA-Csn

Target Information

Target RYK
Alternative Names RYK; D3S3195; JTK5; JTK5A; RYK1; receptor-like tyrosine kinase; receptor like tyrosine kinase

Product Properties

Format Liquid/lyophilized
Shipping It is usually shipped overnight at room temperature in small cardboard boxes. If hot temperatures are expected during transit, they will be shipped in polystyrene containers with gel ice packs.
Handling Advice No special measures are necessary. Keep away from food, drink and animal feedingstuffs.
Storage Plasmid (lyophilized), short-time storage at Room Temperature, recommended store at -20°C or -80°C ; Plasmid (Liquid), blue ice store at 4°C.
COA

Certificate of Analysis Lookup

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