Cas No.: 1952360-91-6
PRODUCT INFORMATION
Description
This is a heterobifunctional, hydrophilic PEGylation linker commonly used as a building block in solid-phase peptide synthesis (SPPS). It features a terminal carboxylic acid and a base-labile Fmoc-protected amine. The carboxylic acid can be activated (e.g., with HBTU or EDC/NHS) to couple with primary amines. The Fmoc group provides robust orthogonal protection, stable to coupling conditions but easily removed with mild base (e.g., piperidine) to expose a new primary amine. The long, 12-unit PEG spacer significantly enhances hydrophilicity and provides a substantial, flexible spacer arm.
Molecular Weight
839.97
Purity
>95.0%
Formula
C₄₂H₆₅NO₁₆
Product Type
Heterobifunctional Crosslinkers ; PEGylation Reagents
Group 1
Other
Group 2
COOH
Form (20 deg.C)
Liquid
Storage Condition
Store under inert gas, -20°C
Molecular Structure
For Research Use Only | Not For Clinical Use
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