Tetramethylrhodamine Methyl Ester Perchlorate Fluorescent Probe (CAT#: OLY-1123-LD15)

Description

Synonyms: N-[6-(Dimethylamino)-9-[2-(methoxycarbonyl)phenyl]-3H-xanthen-3-ylidene]-N-methylmethanaminium Perchlorate. TMRM is a cell-permeant, cationic, and lipophilic fluorescent dye. Due to its positive charge, it accumulates in cellular compartments with a negative membrane potential, most notably the mitochondria. It is a gold-standard probe used to measure the mitochondrial membrane potential (ΔΨm). A decrease in its fluorescence intensity within mitochondria is a key indicator of mitochondrial depolarization, often associated with apoptosis or cellular stress.

Molecular Weight

500.93

Purity

>98.0%

Formula

C₂₅H₂₅ClN₂O₇

Product Type

Fluorescent Probes and Indicators

Ex

548 nm

Em

573 nm

Form (20 deg.C)

Solid

Storage Condition

0-10°C

Molecular Structure