Recombinant Anti-Ad fiber knob x Anti-ITGAV Bispecific Antibody (Triple Body) (TRIB-005)

Recombinant Anti-Ad fiber knob x Anti-ITGAV Bispecific Antibody (Triple Body) is designed to be expressed as two polypeptide chains respectively. The Fd fragment and LC from an anti-Ad fiber knob antibody are both extended with the scFv fragment from an anti-ITGAV antibody. This BsAb can retarget of adenoviral vectors to tumour cells. It can be used in cancer gene therapy to transfer a therapeutic gene into tumour cells aiming at selective and efficient cell killing.

Datasheet INQUIRY

Specifications

Targets

Ad fiber knob & ITGAV

Type

Triple Body

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Colorectal cancer (CRC); Prostate cancer; Ovarian cancer

Targets

Target 1

Ad fiber knob

Alternative Names

Ad fiber knob; Adenovirus fiber knob; adenovirus fiber protein; knob domain of Ad fiber

Target 2

ITGAV

Gene ID

3685

UniProt ID

P06756

Alternative Names

ITGAV; integrin, alpha V; CD51; MSK8; VNRA; VTNR; integrin alpha-V; integrin alphaVbeta3; vitronectin receptor subunit alpha; antigen identified by monoclonal antibody L230; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Related products of "Ad fiber knob & ITGAV"

See other bsAb targets related to "Ad fiber knob"

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-Ad fiber knob x Anti-ITGAV Bispecific Antibody (Triple Body) (TRIB-005). Click the button below to contact us or submit your feedback about this product.

Recombinant Anti-Ad fiber knob x Anti-ITGAV Bispecific Antibody (Triple Body) (CAT#: TRIB-005)

Specifications

Targets

Customer Reviews and Q&As