Recombinant Human Anti-CD2 x Human Anti-TCR (Vβ8) Bispecific Antibody (Diabody-CH3) (BSDBC-H225)

Recombinant Anti-CD2 x Anti-TCR (Vβ8) Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-CD2 and anti-TCR (Vβ8) antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb can activate T cells. It is designed for the research of Tumors therapy.

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Specifications

Targets

CD2 & TCR (Vβ8)

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Mouse

Application

FuncS; Promising therapeutic agent

Related Disease

Tumors

Targets

Target 1

CD2

Gene ID

12481

UniProt ID

P06729

Alternative Names

CD2; CD2 molecule; T11; SRBC; LFA-2; T-cell surface antigen CD2; leukocyte function-associated antigen-2; LFA-3 receptor; rosette receptor; erythrocyte receptor; lymphocyte-function antigen-2; T-cell surface antigen T11/Leu-5; CD2 antigen (p50), sheep red blood cell receptor

Target 2

TCR (Vβ8)

Gene ID

100124664

Alternative Names

Trbv8; T cell receptor beta variable 8; TCR; T-cell receptor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD2 x Human Anti-TCR (Vβ8) Bispecific Antibody (Diabody-CH3) (CAT#: BSDBC-H225)

Specifications

Targets

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