Recombinant Anti-CD2 x Anti-TCR (Vβ8) Bispecific Antibody (scDiabody-Fc) (SCDBF-H225)

Recombinant Anti-CD2 x Anti-TCR (Vβ8) Bispecific Antibody (scDiabody-Fc) is a fusion protein of two scDiabodies with an Fc region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-CD2/anti-TCR (Vβ8) diabody. The scDiabody with two specificities is further fused to the Fc domain to form BsAb with 2+2 antigen-binding valency. This BsAb can activate T cells. It is designed for the research of Tumors therapy.

Datasheet

Specifications

Targets

CD2 & TCR (Vβ8)

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Mouse

Target 1

CD2

Host Animal 1

Human

Target 2

TCR (Vβ8)

Host Animal 2

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Tumors

Targets

Target 1

CD2

Gene ID

12481

UniProt ID

P06729

Alternative Names

CD2; CD2 molecule; T11; SRBC; LFA-2; T-cell surface antigen CD2; leukocyte function-associated antigen-2; LFA-3 receptor; rosette receptor; erythrocyte receptor; lymphocyte-function antigen-2; T-cell surface antigen T11/Leu-5; CD2 antigen (p50), sheep red blood cell receptor

Target 2

TCR (Vβ8)

Gene ID

100124664

Alternative Names

Trbv8; T cell receptor beta variable 8; TCR; T-cell receptor

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