Recombinant Human Anti-FN1 x Human Anti-HSG Bispecific Antibody (Fab-scFv-Fc) (FABVC-H329)

Recombinant Anti-FN1 x Anti-HSG Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-FN1 antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-HSG to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Solid tumors imaging and therapy.

Datasheet INQUIRY

Specifications

Targets

FN1 & HSG

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Pretargeting system for radioimaging and radiotherapy

Related Disease

Solid tumors

Targets

Target 1

FN1

Gene ID

2335

UniProt ID

P02751

Alternative Names

FN1; fibronectin 1; FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; Cold-insoluble globulin; Migration-stimulating factor

Target 2

HSG

Alternative Names

histaminyl-succinyl-glycine; HSG

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-FN1 x Human Anti-HSG Bispecific Antibody (Fab-scFv-Fc) (CAT#: FABVC-H329)

Specifications

Targets

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