Recombinant Anti-FN1 x Anti-HSG Bispecific Antibody (scFv-Fc-scFv) (BSTF-163)

Recombinant Anti-FN1 x Anti-HSG Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-FN1 scFv is fused to the N-terminus of Fc via a hinge region while another anti-HSG scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Solid tumors imaging and therapy.

Datasheet INQUIRY

Specifications

Targets

FN1 & HSG

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Pretargeting system for radioimaging and radiotherapy

Related Disease

Solid tumors

Targets

Target 1

FN1

Gene ID

2335

UniProt ID

P02751

Alternative Names

FN1; fibronectin 1; FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; Cold-insoluble globulin; Migration-stimulating factor

Target 2

HSG

Alternative Names

histaminyl-succinyl-glycine; HSG

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-FN1 x Anti-HSG Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-163)

Specifications

Targets

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