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Recombinant Anti-Malaria Antigen x Anti-TLR1 Bispecific Antibody (Diabody-Fc)  (CAT#: BSDBF-181)

Recombinant Anti-malaria antigen x Anti-TLR1 Bispecific Antibody (Diabody-Fc) is a fusion protein of two diabodies connected together by an Fc region. In a diabody, the two scFvs with short linkers are from anti-malaria antigen and anti-TLR1 antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to the Fc fragment, which results in 2+2 antigen-binding valency and exerts Fc-mediated functions or just extends the half-life. This BsAb can retarget professional antigen-presenting cells (APCs) including DCs or NK cells to malaria antigen. It is designed for the research of Malaria therapy.
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Specifications

Targets
Malaria Antigen & TLR1
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Malaria

Targets

Target 1
Malaria Antigen
Alternative Names
malaria antigen; parasitic protozoans
Target 2
TLR1
Gene ID
UniProt ID
Alternative Names
CD281; TIL; TIL. LPRS5; rsc786; TLR1; Toll-like receptor 1; TLR
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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