Name: Recombinant Human Anti-Nkp30 x Mouse Anti-CD30 Bispecific Antibody (scFv-Fc)
SKU: KN-0725-N63
Rating: 5 (1 reviews)

Recombinant Human Anti-Nkp30 x Mouse Anti-CD30 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-Nkp30 specificity or anti-CD30 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can retarget NK cells to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL) therapy.

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Specifications

Targets

Nkp30 & CD30

Type

scFv-Fc

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL)

Host Animal 1

Human

Host Animal 2

Mouse

Targets

Target 1

Nkp30

Gene ID

259197

UniProt ID

O14931

Alternative Names

NCR3; Natural Cytotoxicity Triggering Receptor 3; CD337; Cluster of Differentiation 337; CLEC2D; C-Type Lectin Domain Family 2 Member D; LY94; Lymphocyte Antigen 94; 1C7; MALS; LY117; NKp30; Activating natural killer receptor p30; Natural killer cell p30-related protein

Target 2

CD30

Gene ID

943

UniProt ID

A5D8T4

Alternative Names

TNFRSF8; tumor necrosis factor receptor superfamily, member 8; CD30; Ki-1; D1S166E; tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-Nkp30 x Mouse Anti-CD30 Bispecific Antibody (scFv-Fc) (CAT#: KN-0725-N63)

Specifications

Targets

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