Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsCannabinoid receptors are a class of cell membrane receptors that belong to the rhodopsin-like G-protein coupled receptor (GPCR) family. They were named because they have an affinity for the agonist delta9-tetrahydrocannabinol (delta9-THC), a ligand found in organic extracts from Cannabis sativa. Typical of G protein-coupled receptors, cannabinoid receptors are characterized by seven transmembrane spanning domains. Currently, two types of cannabinoid receptors have been identified, CB1 receptor and CB2 receptor. CB1R is encoded by the gene CNR1 and consists of 472 amino acids in humans. CB2R is encoded by the gene CNR2, which consists of 360 amino acid in humans. It shares only 44% sequence homology with CB1R at the protein level. Studies have shown that both CB1R and CB2R are coupled through the Gi/o family of proteins and involved in diverse signal transduction mechanisms, including inhibition of adenylyl cyclase, activation of mitogen-activated protein kinase, regulation of calcium and potassium channels (CB1 only), and other signal transduction pathways.
Here, we have described in detail of members of the cannabinoid receptor family, including cannabinoid receptor 1 and cannabinoid receptor 2. To learn more information about functions and applications of CB1R and CB2R, please click the links below.
Aided by our advanced MemDX™ membrane protein production platform, Creative Biolabs is confident in offering diverse target membrane protein products in required formats using various strategies, such as detergent micelles, proteoliposomes, nanodiscs, MP-VLPs, polymers, stable cell line.
Meanwhile, our MemDX™ membrane protein antibody discovery platform can help to discover antibodies against these targets, even fully humanized antibodies, by various approaches such as hybridoma technology, phage display technology. We also present DNA immunization service for anti-membrane protein antibody development. To get more detailed information, please feel free to contact us.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
