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Recombinant Anti-CD3 x Anti-gpA33 Bispecific Antibody (Single-chain Diabody)  (CAT#: SCDB-086)

Recombinant Anti-CD3 x Anti-gpA33 Bispecific Antibody (Single-chain Diabody) is designed to be expressed as one polypeptide chain with four variable domains from two parental antibodies. The middle linker is long enough to form scFv dimers between the two diabody chains. This BsAb can retarget T cells to tumor cells. It is designed for the research of Non-Hodgkin's lymphoma (NHL) therapy.
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Specifications

Targets
CD3 & gpA33
Type
Single-chain Diabody
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Non-Hodgkin's lymphoma (NHL)

Targets

Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
gpA33
Gene ID
UniProt ID
Alternative Names
GPA33; glycoprotein A33; glycoprotein A33 (transmembrane); A33; cell surface A33 antigen; transmembrane glycoprotein A33
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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