Home > Products > CD37 & saporin > Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (Miniantibody)

Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (Miniantibody)  (MNAB-118)

Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-CD37 antibody variable domain is linked to another scFv of an anti-saporin antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can be used in pretargeting system and deliver immunotoxin to tumor cells. It is designed for the research of Non-Hodgkin's lymphoma (NHL); Diffuse large B cell lymphoma (DLBCL); Chronic lymphocytic leukemia (CLL) therapy.

Specifications

Targets
CD37 & saporin
Type
Miniantibody
Species Reactivity
Human
Target 1
CD37
Host Animal 1
Mouse
Target 2
saporin
Host Animal 2
Mouse
Application
FuncS; Pretargeting system for immunotoxin delivery
Related Disease
Non-Hodgkin's lymphoma (NHL); Diffuse large B cell lymphoma (DLBCL); Chronic lymphocytic leukemia (CLL)

Targets

Target 1
CD37
Gene ID
UniProt ID
Alternative Names
CD37; CD37 molecule; GP52-40; TSPAN26; leukocyte antigen CD37; tspan-26; tetraspanin-26; leukocyte surface antigen CD37; cell differentiation antigen 37
Target 2
saporin
Alternative Names
Saporin; Ribosome inactivating protein; RIP

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