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Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (scFv-CH3)  (CAT#: BSFC-118)

Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (scFv-CH3) contains two chains. The anti-CD37 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-saporin scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can be used in pretargeting system and deliver immunotoxin to tumor cells. It is designed for the research of Non-Hodgkin's lymphoma (NHL); Diffuse large B cell lymphoma (DLBCL); Chronic lymphocytic leukemia (CLL) therapy.
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Specifications

Targets
CD37 & saporin
Type
scFv-CH3
Species Reactivity
Human
Application
FuncS; Pretargeting system for immunotoxin delivery
Related Disease
Non-Hodgkin's lymphoma (NHL); Diffuse large B cell lymphoma (DLBCL); Chronic lymphocytic leukemia (CLL)
Host Animal 1
Mouse
Host Animal 2
Mouse

Targets

Target 1
CD37
Gene ID
UniProt ID
Alternative Names
CD37; CD37 molecule; GP52-40; TSPAN26; leukocyte antigen CD37; tspan-26; tetraspanin-26; leukocyte surface antigen CD37; cell differentiation antigen 37
Target 2
saporin
Alternative Names
Saporin; Ribosome inactivating protein; RIP
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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