Home > Products > CD37 & saporin > Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (scFv-IgG)

Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (scFv-IgG)  (BSSG-118)

Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-CD37 antibody variable domain are respectively connected to the N terminus of the anti-saporin IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can be used in pretargeting system and deliver immunotoxin to tumor cells. It is designed for the research of Non-Hodgkin's lymphoma (NHL); Diffuse large B cell lymphoma (DLBCL); Chronic lymphocytic leukemia (CLL) therapy.

Specifications

Targets
CD37 & saporin
Type
Appended IgGs
Species Reactivity
Human
Target 1
CD37
Host Animal 1
Mouse
Target 2
saporin
Host Animal 2
Mouse
Application
FuncS; Pretargeting system for immunotoxin delivery
Related Disease
Non-Hodgkin's lymphoma (NHL); Diffuse large B cell lymphoma (DLBCL); Chronic lymphocytic leukemia (CLL)

Targets

Target 1
CD37
Gene ID
UniProt ID
Alternative Names
CD37; CD37 molecule; GP52-40; TSPAN26; leukocyte antigen CD37; tspan-26; tetraspanin-26; leukocyte surface antigen CD37; cell differentiation antigen 37
Target 2
saporin
Alternative Names
Saporin; Ribosome inactivating protein; RIP

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