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Recombinant Anti-CD37 x Anti-Saporin Bispecific Antibody (scFv-IgG) (CAT#: BSSG-118)
Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-CD37 antibody variable domain are respectively connected to the N terminus of the anti-saporin IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can be used in pretargeting system and deliver immunotoxin to tumor cells. It is designed for the research of Non-Hodgkin's lymphoma (NHL); Diffuse large B cell lymphoma (DLBCL); Chronic lymphocytic leukemia (CLL) therapy.
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