Recombinant Anti-CEA x Anti-DTPA Bispecific Antibody (Diabody-Fc) (BSDBF-137)

Recombinant Anti-CEA x Anti-DTPA Bispecific Antibody (Diabody-Fc) is a fusion protein of two diabodies connected together by an Fc region. In a diabody, the two scFvs with short linkers are from anti-CEA and anti-DTPA antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to the Fc fragment, which results in 2+2 antigen-binding valency and exerts Fc-mediated functions or just extends the half-life. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer imaging and therapy.

Datasheet INQUIRY

Specifications

Targets

CEA & DTPA

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Pretargeting system for radioimaging and radiotherapy

Related Disease

Breast cancer; Ovary cancer; Colon cancer; Lung cancer

Targets

Target 1

CEA

Gene ID

1048

UniProt ID

A0A024R0K5

Alternative Names

CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100

Target 2

DTPA

Alternative Names

diethylenetriaminepentaacetic acid; DTPA; pentetic acid

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CEA x Anti-DTPA Bispecific Antibody (Diabody-Fc) (CAT#: BSDBF-137)

Specifications

Targets

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