Recombinant Anti-CEA x Anti-DTPA Bispecific Antibody (scFv-Fc-scFv) (BSTF-137)

Recombinant Anti-CEA x Anti-DTPA Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-CEA scFv is fused to the N-terminus of Fc via a hinge region while another anti-DTPA scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer imaging and therapy.

Datasheet INQUIRY

Specifications

Targets

CEA & DTPA

Type

scFv-Fc-scFv

Species Reactivity

Human

Application

FuncS; Pretargeting system for radioimaging and radiotherapy

Related Disease

Breast cancer; Ovary cancer; Colon cancer; Lung cancer

Targets

Target 1

CEA

Gene ID

1048

UniProt ID

A0A024R0K5

Alternative Names

CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100

Target 2

DTPA

Alternative Names

diethylenetriaminepentaacetic acid; DTPA; pentetic acid

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CEA x Anti-DTPA Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-137)

Specifications

Targets

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