Home > Products > CEA & DTPA > Recombinant Anti-CEA x Anti-DTPA Bispecific Antibody (Fv-IgG)

Recombinant Anti-CEA x Anti-DTPA Bispecific Antibody (Fv-IgG)  (BSDG-137)

Recombinant Anti-CEA x Anti-DTPA Bispecific Antibody (Fv-IgG) is an appended IgG format, which has 2+2 antigen-binding valency. This dual variable domain IgG is generated by appending variable domains of an anti-CEA IgG with similar domains from an anti-DTPA antibody via short peptide linkers, or vice versa. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer imaging and therapy.

Specifications
Targets
CEA & DTPA
Type
Appended IgGs
Species Reactivity
Human
Target 1
CEA
Host Animal 1
Mouse
Target 2
DTPA
Host Animal 2
Mouse
Application
FuncS; Pretargeting system for radioimaging and radiotherapy
Related Disease
Breast cancer; Ovary cancer; Colon cancer; Lung cancer
Targets
Target 1
CEA
Gene ID
UniProt ID
Alternative Names
CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100
Target 2
DTPA
Alternative Names
diethylenetriaminepentaacetic acid; DTPA; pentetic acid
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