Home > Products > Csl & CD3 > Recombinant Anti-Csl x Anti-CD3 Bispecific Antibody (Fab-scFv-Fc)

Recombinant Anti-Csl x Anti-CD3 Bispecific Antibody (Fab-scFv-Fc)  (CAT#: FABVC-144)

Recombinant Anti-Csl x Anti-CD3 Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-Csl antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-CD3 to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can retarget T cells to tumor cells. It is designed for the research of Breast cancer; Glioma cancaer; Glioblastoma; Multiple myeloma (MM); Leukemia therapy.
Datasheet INQUIRY

Specifications

Targets
Csl & CD3
Type
Fab-Fc Fusion Proteins
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Breast cancer; Glioma cancaer; Glioblastoma; Multiple myeloma (MM); Leukemia

Targets

Target 1
Csl
Gene ID
UniProt ID
Alternative Names
SUH; csl; AOS3; CBF1; KBF2; RBP-J; RBPJK; IGKJRB; RBPSUH; IGKJRB1; recombination signal binding protein for immunoglobulin kappa J region; RBPJ; Lag-1; Suppressor of hairless
Target 2
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
Online Inquiry

Related products of "Csl & CD3"

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-Csl x Anti-CD3 Bispecific Antibody (Fab-scFv-Fc) (FABVC-144). Click the button below to contact us or submit your feedback about this product.