Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Diabody-CH3) (BSDBC-153)

Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-DTPA and anti-GD2 antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors imaging and therapy.

Datasheet INQUIRY

Specifications

Targets

DTPA & GD2

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Pretargeting system for radioimaging and radiotherapy

Related Disease

Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors

Targets

Target 1

DTPA

Alternative Names

diethylenetriaminepentaacetic acid; DTPA; pentetic acid

Target 2

GD2

Alternative Names

Ganglioside GD2; GD2; Ganglioside; Disialoganglioside GD2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Diabody-CH3) (CAT#: BSDBC-153)

Specifications

Targets

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