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Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Tandem scFv-Fc)  (CAT#: BSFVF-153)

Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Tandem scFv-Fc) is designed to be expressed as a homodimer, which has 2+2 antigen-binding valency. This format consists of one Fc region and two tandem scFv fragments, in which the anti-DTPA/GD2 tandem scFv is fused to the Fc domain. The engineered fragment format is used to extend the half-life. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors imaging and therapy.
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Specifications

Targets
DTPA & GD2
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Application
FuncS; Pretargeting system for radioimaging and radiotherapy
Related Disease
Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors

Targets

Target 1
DTPA
Alternative Names
diethylenetriaminepentaacetic acid; DTPA; pentetic acid
Target 2
GD2
Alternative Names
Ganglioside GD2; GD2; Ganglioside; Disialoganglioside GD2
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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