Home > Products > DTPA & GD2 > Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Fab-Fv)

Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Fab-Fv)  (FABFV-153)

Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Fab-Fv) is designed to be expressed as two polypeptide chains. The heavy chain Fd fragment and light chain of an anti-DTPA antibody are fused with the VL and VH domains of an anti-GD2 antibody respectively. It can form natural in vivo heterodimerization. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors imaging and therapy.

Specifications

Targets
DTPA & GD2
Type
Fab-Fv
Species Reactivity
Human
Target 1
DTPA
Host Animal 1
Mouse
Target 2
GD2
Host Animal 2
Mouse
Application
FuncS; Pretargeting system for radioimaging and radiotherapy
Related Disease
Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors

Targets

Target 1
DTPA
Alternative Names
diethylenetriaminepentaacetic acid; DTPA; pentetic acid
Target 2
GD2
Alternative Names
Ganglioside GD2; GD2; Ganglioside; Disialoganglioside GD2

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