Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Diabody-Fc) (BSDBF-153)

Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Diabody-Fc) is a fusion protein of two diabodies connected together by an Fc region. In a diabody, the two scFvs with short linkers are from anti-DTPA and anti-GD2 antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to the Fc fragment, which results in 2+2 antigen-binding valency and exerts Fc-mediated functions or just extends the half-life. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors imaging and therapy.

Datasheet INQUIRY

Specifications

Targets

DTPA & GD2

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Pretargeting system for radioimaging and radiotherapy

Related Disease

Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors

Targets

Target 1

DTPA

Alternative Names

diethylenetriaminepentaacetic acid; DTPA; pentetic acid

Target 2

GD2

Alternative Names

Ganglioside GD2; GD2; Ganglioside; Disialoganglioside GD2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Diabody-Fc) (CAT#: BSDBF-153)

Specifications

Targets

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