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CD22 Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
BSFAB-MEL003 Recombinant Anti-CD19 x Anti-CD22 Tandem Fab-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Mouse CD22 Mouse Inquiry
BSFAB-BGN022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem Fab-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Human CD22 Human Inquiry
BSFAB-BGN021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem Fab-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Human CD22 Human Inquiry
BSFAB-BGN004 Recombinant Anti-CD20 x Anti-CD22 Tandem Fab-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Mouse CD22 Mouse Inquiry
BSFAB-BGN003 Recombinant Anti-CD19 x Anti-CD22 Tandem Fab-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Mouse CD22 Mouse Inquiry
BSFAB-ABR022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Human CD22 Human Inquiry
BSFAB-ABR021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Human CD22 Human Inquiry
BSFAB-ABR004 Recombinant Anti-CD20 x Anti-CD22 Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Mouse CD22 Mouse Inquiry
BSFAB-ABR003 Recombinant Anti-CD19 x Anti-CD22 Tandem Fab-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Mouse CD22 Mouse Inquiry
BSFAB-PAP022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem Fab-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Human CD22 Human Inquiry
BSFAB-PAP021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem Fab-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Human CD22 Human Inquiry
BSFAB-PAP004 Recombinant Anti-CD20 x Anti-CD22 Tandem Fab-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Mouse CD22 Mouse Inquiry
BSFAB-PAP003 Recombinant Anti-CD19 x Anti-CD22 Tandem Fab-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Mouse CD22 Mouse Inquiry
BSFAB-SAP022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem Fab-SAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Human CD22 Human Inquiry
BSFAB-SAP021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem Fab-SAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Human CD22 Human Inquiry
BSFAB-SAP004 Recombinant Anti-CD20 x Anti-CD22 Tandem Fab-SAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Mouse CD22 Mouse Inquiry
BSFAB-SAP003 Recombinant Anti-CD19 x Anti-CD22 Tandem Fab-SAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Mouse CD22 Mouse Inquiry
BSFAB-RTA022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem Fab-RTA immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Human CD22 Human Inquiry
BSFAB-RTA021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem Fab-RTA immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Human CD22 Human Inquiry
BSFAB-RTA004 Recombinant Anti-CD20 x Anti-CD22 Tandem Fab-RTA immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Mouse CD22 Mouse Inquiry
BSFAB-RTA003 Recombinant Anti-CD19 x Anti-CD22 Tandem Fab-RTA immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Mouse CD22 Mouse Inquiry
BSFAB-GEL022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem Fab-Gel immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Human CD22 Human Inquiry
BSFAB-GEL021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem Fab-Gel immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Human CD22 Human Inquiry
BSFAB-GEL004 Recombinant Anti-CD20 x Anti-CD22 Tandem Fab-Gel immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Mouse CD22 Mouse Inquiry
BSFAB-GEL003 Recombinant Anti-CD19 x Anti-CD22 Tandem Fab-Gel immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Mouse CD22 Mouse Inquiry
BSFAB-PE022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Human CD22 Human Inquiry
BSFAB-PE021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Human CD22 Human Inquiry
BSFAB-PE004 Recombinant Anti-CD20 x Anti-CD22 Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Mouse CD22 Mouse Inquiry
BSFAB-PE003 Recombinant Anti-CD19 x Anti-CD22 Tandem Fab-PE immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Mouse CD22 Mouse Inquiry
BSFAB-DT022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Human CD22 Human Inquiry
BSFAB-DT021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Human CD22 Human Inquiry
BSFAB-DT004 Recombinant Anti-CD20 x Anti-CD22 Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Mouse CD22 Mouse Inquiry
BSFAB-DT003 Recombinant Anti-CD19 x Anti-CD22 Tandem Fab-DT immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Mouse CD22 Mouse Inquiry
BSFV-SAR022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Human CD22 Human Inquiry
BSFV-SAR021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Human CD22 Human Inquiry
BSFV-SAR004 Recombinant Anti-CD20 x Anti-CD22 Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Mouse CD22 Mouse Inquiry
BSFV-SAR003 Recombinant Anti-CD19 x Anti-CD22 Tandem scFv-SAR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Mouse CD22 Mouse Inquiry
BSFV-NGB022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Human CD22 Human Inquiry
BSFV-NGB021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Human CD22 Human Inquiry
BSFV-NGB004 Recombinant Anti-CD20 x Anti-CD22 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Mouse CD22 Mouse Inquiry
BSFV-NGB003 Recombinant Anti-CD19 x Anti-CD22 Tandem scFv-NGB immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Mouse CD22 Mouse Inquiry
BSFV-MEL022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Human CD22 Human Inquiry
BSFV-MEL021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Human CD22 Human Inquiry
BSFV-MEL004 Recombinant Anti-CD20 x Anti-CD22 Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Mouse CD22 Mouse Inquiry
BSFV-MEL003 Recombinant Anti-CD19 x Anti-CD22 Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Mouse CD22 Mouse Inquiry
BSFV-BGN022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Human CD22 Human Inquiry
BSFV-BGN021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Human CD22 Human Inquiry
BSFV-BGN004 Recombinant Anti-CD20 x Anti-CD22 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Mouse CD22 Mouse Inquiry
BSFV-BGN003 Recombinant Anti-CD19 x Anti-CD22 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Mouse CD22 Mouse Inquiry
BSFV-ABR022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Human CD22 Human Inquiry
BSFV-ABR021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Human CD22 Human Inquiry
BSFV-ABR004 Recombinant Anti-CD20 x Anti-CD22 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Mouse CD22 Mouse Inquiry
BSFV-ABR003 Recombinant Anti-CD19 x Anti-CD22 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Mouse CD22 Mouse Inquiry
BSFV-PAP022 Recombinant Human Anti-CD20 x Human Anti-CD22 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD20 Human CD22 Human Inquiry
BSFV-PAP021 Recombinant Human Anti-CD19 x Human Anti-CD22 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CD19 Human CD22 Human Inquiry
SCDB-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD20 Human CD22 Human Inquiry
SCDB-H214 Recombinant Human Anti-CD19 x Anti-CD22 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD19 Human CD22 Human Inquiry
FABIG-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD20 Human CD22 Human Inquiry
FABIG-H214 Recombinant Human Anti-CD19 x Anti-CD22 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD19 Human CD22 Human Inquiry
TRIB-H226 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD20 Human CD22 Human Inquiry
TRIB-H216 Recombinant Human Anti-CD19 x Anti-CD22 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD19 Human CD22 Human Inquiry
BSIG-H224 Human Anti-CD20 x Anti-CD22 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 Human CD22 Human Inquiry
BSIG-H214 Human Anti-CD19 x Anti-CD22 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD19 Human CD22 Human Inquiry
CROSSAB-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (CrossMab) Human CrossMab CD20 Human CD22 Human Inquiry
CROSSAB-H214 Recombinant Human Anti-CD19 x Anti-CD22 Bispecific Antibody (CrossMab) Human CrossMab CD19 Human CD22 Human Inquiry
IGFV-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 Human CD22 Human Inquiry
IGFV-H214 Recombinant Human Anti-CD19 x Anti-CD22 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD19 Human CD22 Human Inquiry
BSDB-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (Diabody) Human Diabody CD20 Human CD22 Human Inquiry
BSDB-H214 Recombinant Human Anti-CD19 x Anti-CD22 Bispecific Antibody (Diabody) Human Diabody CD19 Human CD22 Human Inquiry
BSFAB-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 Human CD22 Human Inquiry
BSFAB-H214 Recombinant Human Anti-CD19 x Anti-CD22 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 Human CD22 Human Inquiry
BSFV-H224 Recombinant Human Anti-CD20 x Anti-CD22 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 Human CD22 Human Inquiry
BSFV-H214 Recombinant Human Anti-CD19 x Anti-CD22 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 Human CD22 Human Inquiry
SCDB-053 Recombinant Anti-CD22 x Anti-Saporin Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD22 Mouse Saporin Mouse Inquiry
SCDB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD20 Mouse CD22 Mouse Inquiry
SCDB-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD19 Mouse CD22 Mouse Inquiry
FABIG-053 Recombinant Anti-CD22 x Anti-Saporin Bispecific Antibody (Fab-IgG) Human Fab-IgG CD22 Mouse Saporin Mouse Inquiry
FABIG-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD20 Mouse CD22 Mouse Inquiry
FABIG-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD19 Mouse CD22 Mouse Inquiry
TRIB-053 Recombinant Anti-CD22 x Anti-Saporin Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD22 Mouse Saporin Mouse Inquiry
TRIB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD20 Mouse CD22 Mouse Inquiry
TRIB-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD19 Mouse CD22 Mouse Inquiry
BSIG-053 Anti-CD22 x Anti-Saporin Bispecific Antibody (IgG-IgG) Human IgG-IgG CD22 Mouse Saporin Mouse Inquiry
BSIG-049 Anti-CD20 x Anti-CD22 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD20 Mouse CD22 Mouse Inquiry
BSIG-039 Anti-CD19 x Anti-CD22 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD19 Mouse CD22 Mouse Inquiry
CROSSAB-053 Recombinant Anti-CD22 x Anti-Saporin Bispecific Antibody (CrossMab) Human CrossMab CD22 Mouse Saporin Mouse Inquiry
CROSSAB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (CrossMab) Human CrossMab CD20 Mouse CD22 Mouse Inquiry
CROSSAB-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (CrossMab) Human CrossMab CD19 Mouse CD22 Mouse Inquiry
IGFV-053 Recombinant Anti-CD22 x Anti-Saporin Bispecific Antibody (IgG-scFv) Human IgG-scFv CD22 Mouse Saporin Mouse Inquiry
IGFV-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD20 Mouse CD22 Mouse Inquiry
IGFV-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD19 Mouse CD22 Mouse Inquiry
BSDB-053 Recombinant Anti-CD22 x Anti-Saporin Bispecific Antibody (Diabody) Human Diabody CD22 Mouse Saporin Mouse Inquiry
BSDB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Diabody) Human Diabody CD20 Mouse CD22 Mouse Inquiry
BSDB-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (Diabody) Human Diabody CD19 Mouse CD22 Mouse Inquiry
BSFAB-053 Recombinant Anti-CD22 x Anti-Saporin Bispecific Antibody (Tandem Fab) Human Tandem Fab CD22 Mouse Saporin Mouse Inquiry
BSFAB-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD20 Mouse CD22 Mouse Inquiry
BSFAB-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD19 Mouse CD22 Mouse Inquiry
BSFV-053 Recombinant Anti-CD22 x Anti-Saporin Bispecific Antibody (Tandem scFv) Human Tandem scFv CD22 Mouse Saporin Mouse Inquiry
BSFV-049 Recombinant Anti-CD20 x Anti-CD22 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD20 Mouse CD22 Mouse Inquiry
BSFV-039 Recombinant Anti-CD19 x Anti-CD22 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD19 Mouse CD22 Mouse Inquiry

Background

CD22, also referred to as cluster of differentiation-22, is a transmembrane protein that binds to sugars. It has a molecular weight of 140 kDa and is classified as a member of the SIGLEC lectin family. CD22 is designated as an "inhibitory receptor" due to the presence of four ITIMs in its cytoplasmic tail, thus playing a crucial role in preventing excessive immune system activity and the onset of autoimmune disorders. CD22 is expressed on the surface of both mature B cells and certain immature B cells. The fact that CD22 is unique to B cells makes it an ideal target for B-cell immunotherapy. Moreover, CD22 may make "trans" connections with ligands on other cells or form "cis" connections with itself or other cell surface molecules on B cells when surface IgM (sIgM) and CD45 express their ligands.

Fig.1 CD22's function in modulating BCR/TLR-mediated B cell responses to autoantigens. (Clark and Natalia, 2018)Fig.1 CD22's function in modulating BCR/TLR-mediated B cell responses to autoantigens.1

Reference

  1. Clark, Edward A., and Natalia V. Giltiay. "CD22: a regulator of innate and adaptive B cell responses and autoimmunity." Frontiers in Immunology 9 (2018): 2235.
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