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CD4 Bispecific Antibodies
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CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
FVTIG-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD3 Human CD4 Human Inquiry
FVTIG-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD2 Mouse CD4 Mouse Inquiry
FVTIG-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (scFv4-Ig) Human scFv4-Ig CD3 Mouse CD4 Mouse Inquiry
BSSG-H355 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (scFv-IgG) Human scFv-IgG CD2 Human CD4 Human Inquiry
BSSG-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (scFv-IgG) Human scFv-IgG CD3 Human CD4 Human Inquiry
BSSG-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (scFv-IgG) Human scFv-IgG CD2 Mouse CD4 Mouse Inquiry
BSSG-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (scFv-IgG) Human scFv-IgG CD3 Mouse CD4 Mouse Inquiry
IGLFV-H355 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD2 Human CD4 Human Inquiry
IGLFV-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD3 Human CD4 Human Inquiry
IGLFV-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD2 Mouse CD4 Mouse Inquiry
IGLFV-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv CD3 Mouse CD4 Mouse Inquiry
BSGV-H355 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD2 Mouse CD4 Mouse Inquiry
BSGV-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD3 Mouse CD4 Mouse Inquiry
BSGV-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD2 Mouse CD4 Mouse Inquiry
BSGV-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (IgG-Fv) Human IgG-Fv CD3 Mouse CD4 Mouse Inquiry
BSDG-H355 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (Fv-IgG) Human Fv-IgG CD2 Human CD4 Human Inquiry
BSDG-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (Fv-IgG) Human Fv-IgG CD3 Human CD4 Human Inquiry
BSDG-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (Fv-IgG) Human Fv-IgG CD2 Mouse CD4 Mouse Inquiry
BSDG-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Fv-IgG) Human Fv-IgG CD3 Mouse CD4 Mouse Inquiry
BABFV-H355 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD2 Human CD4 Human Inquiry
BABFV-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD3 Human CD4 Human Inquiry
BABFV-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD2 Mouse CD4 Mouse Inquiry
BABFV-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 CD3 Mouse CD4 Mouse Inquiry
FABVC-H355 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD2 Human CD4 Human Inquiry
FABVC-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD3 Human CD4 Human Inquiry
FABVC-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD2 Mouse CD4 Mouse Inquiry
FABVC-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc CD3 Mouse CD4 Mouse Inquiry
SCDBC-H355 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD2 Human CD4 Human Inquiry
SCDBC-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD3 Human CD4 Human Inquiry
SCDBC-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD2 Mouse CD4 Mouse Inquiry
SCDBC-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 CD3 Mouse CD4 Mouse Inquiry
BSDBC-H355 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD2 Human CD4 Human Inquiry
BSDBC-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD3 Human CD4 Human Inquiry
BSDBC-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD2 Mouse CD4 Mouse Inquiry
BSDBC-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 CD3 Mouse CD4 Mouse Inquiry
SCDBF-H355 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD2 Human CD4 Human Inquiry
SCDBF-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD3 Human CD4 Human Inquiry
SCDBF-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD2 Mouse CD4 Mouse Inquiry
SCDBF-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc CD3 Mouse CD4 Mouse Inquiry
BSFVF-H355 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD2 Human CD4 Human Inquiry
BSFVF-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD3 Human CD4 Human Inquiry
BSFVF-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD2 Mouse CD4 Mouse Inquiry
BSFVF-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc CD3 Mouse CD4 Mouse Inquiry
BSDBF-H355 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD2 Human CD4 Human Inquiry
BSDBF-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD3 Human CD4 Human Inquiry
BSDBF-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD2 Mouse CD4 Mouse Inquiry
BSDBF-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Diabody-Fc) Human Diabody-Fc CD3 Mouse CD4 Mouse Inquiry
BSTF-H355 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD2 Mouse CD4 Mouse Inquiry
BSTF-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD3 Mouse CD4 Mouse Inquiry
BSTF-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD2 Mouse CD4 Mouse Inquiry
BSTF-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv CD3 Mouse CD4 Mouse Inquiry
BSCFV-H355 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (scFv-Fc) Human scFv-Fc CD2 Mouse CD4 Mouse Inquiry
BSCFV-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (scFv-Fc) Human scFv-Fc CD3 Mouse CD4 Mouse Inquiry
BSCFV-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (scFv-Fc) Human scFv-Fc CD2 Mouse CD4 Mouse Inquiry
BSCFV-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (scFv-Fc) Human scFv-Fc CD3 Mouse CD4 Mouse Inquiry
MNAB-H355 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (Miniantibody) Human Miniantibody CD2 Mouse CD4 Mouse Inquiry
MNAB-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (Miniantibody) Human Miniantibody CD3 Mouse CD4 Mouse Inquiry
MNAB-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (Miniantibody) Human Miniantibody CD2 Mouse CD4 Mouse Inquiry
MNAB-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Miniantibody) Human Miniantibody CD3 Mouse CD4 Mouse Inquiry
BSFC-H355 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD2 Mouse CD4 Mouse Inquiry
BSFC-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD3 Mouse CD4 Mouse Inquiry
BSFC-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD2 Mouse CD4 Mouse Inquiry
BSFC-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (scFv-CH3) Human scFv-CH3 CD3 Mouse CD4 Mouse Inquiry
BSCC-H355 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD2 Mouse CD4 Mouse Inquiry
BSCC-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD3 Mouse CD4 Mouse Inquiry
BSCC-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD2 Mouse CD4 Mouse Inquiry
BSCC-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL CD3 Mouse CD4 Mouse Inquiry
BIBD-H355 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (Bibody) Human Bibody CD2 Mouse CD4 Mouse Inquiry
BIBD-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (Bibody) Human Bibody CD3 Mouse CD4 Mouse Inquiry
BIBD-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (Bibody) Human Bibody CD2 Mouse CD4 Mouse Inquiry
BIBD-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Bibody) Human Bibody CD3 Mouse CD4 Mouse Inquiry
FABFV-H354 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD2 Human CD4 Human Inquiry
FABFV-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Human CD4 Human Inquiry
FABFV-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD2 Mouse CD4 Mouse Inquiry
FABFV-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Fab-Fv) Human Fab-Fv CD3 Mouse CD4 Mouse Inquiry
MiniB-H355 Recombinant Human Anti-CD2 x Human Anti-CD4 Bispecific Antibody (Minibody) Human Minibody CD2 Human CD4 Human Inquiry
MiniB-H243 Recombinant Human Anti-CD3 x Human Anti-CD4 Bispecific Antibody (Minibody) Human Minibody CD3 Human CD4 Human Inquiry
MiniB-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (Minibody) Human Minibody CD2 Mouse CD4 Mouse Inquiry
MiniB-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Minibody) Human Minibody CD3 Mouse CD4 Mouse Inquiry
BSFV-193 Recombinant Anti-CD2 x Anti-CD4 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD2 Mouse CD4 Mouse Inquiry
SCTB-H137 Recombinant Human Anti-CD4 x Human Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Human CD4 Human Inquiry
SCDB-H241 Recombinant Human Anti-CD3 x Anti-CD4 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Human CD4 Human Inquiry
FABIG-H241 Recombinant Human Anti-CD3 x Anti-CD4 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Human CD4 Human Inquiry
TRIB-H243 Recombinant Human Anti-CD3 x Anti-CD4 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Human CD4 Human Inquiry
BSIG-H241 Human Anti-CD3 x Anti-CD4 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Human CD4 Human Inquiry
CROSSAB-H241 Recombinant Human Anti-CD3 x Anti-CD4 Bispecific Antibody (CrossMab) Human CrossMab CD3 Human CD4 Human Inquiry
IGFV-H241 Recombinant Human Anti-CD3 x Anti-CD4 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Human CD4 Human Inquiry
BSDB-H241 Recombinant Human Anti-CD3 x Anti-CD4 Bispecific Antibody (Diabody) Human Diabody CD3 Human CD4 Human Inquiry
BSFAB-H241 Recombinant Human Anti-CD3 x Anti-CD4 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Human CD4 Human Inquiry
BSFV-H241 Recombinant Human Anti-CD3 x Anti-CD4 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Human CD4 Human Inquiry
SCTB-039 Recombinant Anti-CD4 x Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Mouse CD4 Mouse Inquiry
SCDB-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Mouse CD4 Mouse Inquiry
FABIG-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Mouse CD4 Mouse Inquiry
TRIB-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Mouse CD4 Mouse Inquiry
BSIG-067 Anti-CD3 x Anti-CD4 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Mouse CD4 Mouse Inquiry
CROSSAB-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (CrossMab) Human CrossMab CD3 Mouse CD4 Mouse Inquiry
IGFV-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Mouse CD4 Mouse Inquiry
BSDB-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Diabody) Human Diabody CD3 Mouse CD4 Mouse Inquiry
BSFAB-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse CD4 Mouse Inquiry
BSFV-067 Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse CD4 Mouse Inquiry

Background

The CD4 receptor is a 55 kDa type I integrated transmembrane glycoprotein in the immunoglobulin superfamily. It is also known as the primary entry receptor for HIV. CD4 is also a co-receptor for human and primate immunodeficiency viruses (HIV-1, HIV-2, and SIV). CD4 receptor plays a crucial role in the immune system, especially during T cell activation. It can complete adhesion or signal transduction functions, enhancing T-cell sensitivity to antigens. In addition, the CD4 receptor is believed to play a role in helper T cell differentiation and T cell chemotaxis towards IL-16. It is crucial for the development and function of CD4+ T cell subsets, and also serves as a receptor for human immunodeficiency virus.

Fig.1 The CD4 receptor has an intercellular adhesion function during T cell activation. (Claeys, 2019) Fig.1 The CD4 receptor has an intercellular adhesion function during T cell activation.1

Reference

  1. Claeys, Elisa, and Kurt Vermeire. "The CD4 receptor: An indispensable protein in T cell activation and a promising target for immunosuppression." Archives of Microbiology & Immunology 3.3 (2019): 133-150.
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