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GD2 Bispecific Antibodies
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Product List

CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
BSFV-MEL005 Recombinant Anti-CEA x Anti-GD2 Tandem scFv-MEL immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CEA Mouse GD2 Mouse Inquiry
BSFV-BGN023 Recombinant Human Anti-CEA x Human Anti-GD2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CEA Human GD2 Human Inquiry
BSFV-BGN005 Recombinant Anti-CEA x Anti-GD2 Tandem scFv-BGN immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CEA Mouse GD2 Mouse Inquiry
BSFV-ABR023 Recombinant Human Anti-CEA x Human Anti-GD2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CEA Human GD2 Human Inquiry
BSFV-ABR005 Recombinant Anti-CEA x Anti-GD2 Tandem scFv-ABR immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CEA Mouse GD2 Mouse Inquiry
BSFV-PAP023 Recombinant Human Anti-CEA x Human Anti-GD2 Tandem scFv-PAP immunotoxin (Bispecific Immunotoxin) Human Bispecific Immunotoxin CEA Human GD2 Human Inquiry
SCTB-H189 Recombinant Human Anti-GD2 x Human Anti-CD64 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD64 Human GD2 Human Inquiry
SCTB-H154 Recombinant Human Anti-GD2 x Human Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Human GD2 Human Inquiry
SCTB-H113 Recombinant Human Anti-GD2 x Human Anti-CD16 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD16 Human GD2 Human Inquiry
SCDB-H319 Recombinant Human Anti-DTPA x Anti-GD2 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody DTPA Human GD2 Human Inquiry
SCDB-H307 Recombinant Human Anti-CEA x Anti-GD2 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CEA Human GD2 Human Inquiry
SCDB-H298 Recombinant Human Anti-CD64 x Anti-GD2 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD64 Human GD2 Human Inquiry
SCDB-H257 Recombinant Human Anti-CD3 x Anti-GD2 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Human GD2 Human Inquiry
SCDB-H212 Recombinant Human Anti-CD16 x Anti-GD2 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD16 Human GD2 Human Inquiry
FABIG-H319 Recombinant Human Anti-DTPA x Anti-GD2 Bispecific Antibody (Fab-IgG) Human Fab-IgG DTPA Human GD2 Human Inquiry
FABIG-H307 Recombinant Human Anti-CEA x Anti-GD2 Bispecific Antibody (Fab-IgG) Human Fab-IgG CEA Human GD2 Human Inquiry
FABIG-H298 Recombinant Human Anti-CD64 x Anti-GD2 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD64 Human GD2 Human Inquiry
FABIG-H257 Recombinant Human Anti-CD3 x Anti-GD2 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Human GD2 Human Inquiry
FABIG-H212 Recombinant Human Anti-CD16 x Anti-GD2 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD16 Human GD2 Human Inquiry
TRIB-H309 Recombinant Human Anti-CEA x Anti-GD2 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CEA Human GD2 Human Inquiry
TRIB-H300 Recombinant Human Anti-CD64 x Anti-GD2 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD64 Human GD2 Human Inquiry
TRIB-H259 Recombinant Human Anti-CD3 x Anti-GD2 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Human GD2 Human Inquiry
TRIB-H214 Recombinant Human Anti-CD16 x Anti-GD2 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD16 Human GD2 Human Inquiry
BSIG-H319 Human Anti-DTPA x Anti-GD2 Bispecific Antibody (IgG-IgG) Human IgG-IgG DTPA Human GD2 Human Inquiry
BSIG-H307 Human Anti-CEA x Anti-GD2 Bispecific Antibody (IgG-IgG) Human IgG-IgG CEA Human GD2 Human Inquiry
BSIG-H298 Human Anti-CD64 x Anti-GD2 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD64 Human GD2 Human Inquiry
BSIG-H257 Human Anti-CD3 x Anti-GD2 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Human GD2 Human Inquiry
BSIG-H212 Human Anti-CD16 x Anti-GD2 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD16 Human GD2 Human Inquiry
CROSSAB-H319 Recombinant Human Anti-DTPA x Anti-GD2 Bispecific Antibody (CrossMab) Human CrossMab DTPA Human GD2 Human Inquiry
CROSSAB-H307 Recombinant Human Anti-CEA x Anti-GD2 Bispecific Antibody (CrossMab) Human CrossMab CEA Human GD2 Human Inquiry
CROSSAB-H298 Recombinant Human Anti-CD64 x Anti-GD2 Bispecific Antibody (CrossMab) Human CrossMab CD64 Human GD2 Human Inquiry
CROSSAB-H257 Recombinant Human Anti-CD3 x Anti-GD2 Bispecific Antibody (CrossMab) Human CrossMab CD3 Human GD2 Human Inquiry
CROSSAB-H212 Recombinant Human Anti-CD16 x Anti-GD2 Bispecific Antibody (CrossMab) Human CrossMab CD16 Human GD2 Human Inquiry
IGFV-H319 Recombinant Human Anti-DTPA x Anti-GD2 Bispecific Antibody (IgG-scFv) Human IgG-scFv DTPA Human GD2 Human Inquiry
IGFV-H307 Recombinant Human Anti-CEA x Anti-GD2 Bispecific Antibody (IgG-scFv) Human IgG-scFv CEA Human GD2 Human Inquiry
IGFV-H298 Recombinant Human Anti-CD64 x Anti-GD2 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD64 Human GD2 Human Inquiry
IGFV-H257 Recombinant Human Anti-CD3 x Anti-GD2 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Human GD2 Human Inquiry
IGFV-H212 Recombinant Human Anti-CD16 x Anti-GD2 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD16 Human GD2 Human Inquiry
BSDB-H319 Recombinant Human Anti-DTPA x Anti-GD2 Bispecific Antibody (Diabody) Human Diabody DTPA Human GD2 Human Inquiry
BSDB-H307 Recombinant Human Anti-CEA x Anti-GD2 Bispecific Antibody (Diabody) Human Diabody CEA Human GD2 Human Inquiry
BSDB-H298 Recombinant Human Anti-CD64 x Anti-GD2 Bispecific Antibody (Diabody) Human Diabody CD64 Human GD2 Human Inquiry
BSDB-H257 Recombinant Human Anti-CD3 x Anti-GD2 Bispecific Antibody (Diabody) Human Diabody CD3 Human GD2 Human Inquiry
BSDB-H212 Recombinant Human Anti-CD16 x Anti-GD2 Bispecific Antibody (Diabody) Human Diabody CD16 Human GD2 Human Inquiry
BSFAB-H319 Recombinant Human Anti-DTPA x Anti-GD2 Bispecific Antibody (Tandem Fab) Human Tandem Fab DTPA Human GD2 Human Inquiry
BSFAB-H307 Recombinant Human Anti-CEA x Anti-GD2 Bispecific Antibody (Tandem Fab) Human Tandem Fab CEA Human GD2 Human Inquiry
BSFAB-H298 Recombinant Human Anti-CD64 x Anti-GD2 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD64 Human GD2 Human Inquiry
BSFAB-H257 Recombinant Human Anti-CD3 x Anti-GD2 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Human GD2 Human Inquiry
BSFAB-H212 Recombinant Human Anti-CD16 x Anti-GD2 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD16 Human GD2 Human Inquiry
BSFV-H307 Recombinant Human Anti-CEA x Anti-GD2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CEA Human GD2 Human Inquiry
BSFV-H298 Recombinant Human Anti-CD64 x Anti-GD2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD64 Human GD2 Human Inquiry
BSFV-H257 Recombinant Human Anti-CD3 x Anti-GD2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Human GD2 Human Inquiry
BSFV-H212 Recombinant Human Anti-CD16 x Anti-GD2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD16 Human GD2 Human Inquiry
SCTB-094 Recombinant Anti-GD2 x Anti-CD64 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD64 Mouse GD2 Mouse Inquiry
SCTB-056 Recombinant Anti-GD2 x Anti-CD3 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD3 Mouse GD2 Mouse Inquiry
SCTB-013 Recombinant Anti-GD2 x Anti-CD16 Bispecific Antibody (Single-chain Triplebody) Human Single-chain Triplebody CD16 Mouse GD2 Mouse Inquiry
SCDB-153 Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody DTPA Mouse GD2 Mouse Inquiry
SCDB-138 Recombinant Anti-CEA x Anti-GD2 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CEA Mouse GD2 Mouse Inquiry
SCDB-126 Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD64 Mouse GD2 Mouse Inquiry
SCDB-083 Recombinant Anti-CD3 x Anti-GD2 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD3 Mouse GD2 Mouse Inquiry
SCDB-037 Recombinant Anti-CD16 x Anti-GD2 Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody CD16 Mouse GD2 Mouse Inquiry
FABIG-153 Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Fab-IgG) Human Fab-IgG DTPA Mouse GD2 Mouse Inquiry
FABIG-138 Recombinant Anti-CEA x Anti-GD2 Bispecific Antibody (Fab-IgG) Human Fab-IgG CEA Mouse GD2 Mouse Inquiry
FABIG-126 Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD64 Mouse GD2 Mouse Inquiry
FABIG-083 Recombinant Anti-CD3 x Anti-GD2 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD3 Mouse GD2 Mouse Inquiry
FABIG-037 Recombinant Anti-CD16 x Anti-GD2 Bispecific Antibody (Fab-IgG) Human Fab-IgG CD16 Mouse GD2 Mouse Inquiry
TRIB-153 Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv DTPA Mouse GD2 Mouse Inquiry
TRIB-138 Recombinant Anti-CEA x Anti-GD2 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CEA Mouse GD2 Mouse Inquiry
TRIB-126 Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD64 Mouse GD2 Mouse Inquiry
TRIB-083 Recombinant Anti-CD3 x Anti-GD2 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD3 Mouse GD2 Mouse Inquiry
TRIB-037 Recombinant Anti-CD16 x Anti-GD2 Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv CD16 Mouse GD2 Mouse Inquiry
BSIG-153 Anti-DTPA x Anti-GD2 Bispecific Antibody (IgG-IgG) Human IgG-IgG DTPA Mouse GD2 Mouse Inquiry
BSIG-138 Anti-CEA x Anti-GD2 Bispecific Antibody (IgG-IgG) Human IgG-IgG CEA Mouse GD2 Mouse Inquiry
BSIG-126 Anti-CD64 x Anti-GD2 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD64 Mouse GD2 Mouse Inquiry
BSIG-083 Anti-CD3 x Anti-GD2 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD3 Mouse GD2 Mouse Inquiry
BSIG-037 Anti-CD16 x Anti-GD2 Bispecific Antibody (IgG-IgG) Human IgG-IgG CD16 Mouse GD2 Mouse Inquiry
CROSSAB-153 Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (CrossMab) Human CrossMab DTPA Mouse GD2 Mouse Inquiry
CROSSAB-138 Recombinant Anti-CEA x Anti-GD2 Bispecific Antibody (CrossMab) Human CrossMab CEA Mouse GD2 Mouse Inquiry
CROSSAB-126 Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (CrossMab) Human CrossMab CD64 Mouse GD2 Mouse Inquiry
CROSSAB-083 Recombinant Anti-CD3 x Anti-GD2 Bispecific Antibody (CrossMab) Human CrossMab CD3 Mouse GD2 Mouse Inquiry
CROSSAB-037 Recombinant Anti-CD16 x Anti-GD2 Bispecific Antibody (CrossMab) Human CrossMab CD16 Mouse GD2 Mouse Inquiry
IGFV-153 Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (IgG-scFv) Human IgG-scFv DTPA Mouse GD2 Mouse Inquiry
IGFV-138 Recombinant Anti-CEA x Anti-GD2 Bispecific Antibody (IgG-scFv) Human IgG-scFv CEA Mouse GD2 Mouse Inquiry
IGFV-126 Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD64 Mouse GD2 Mouse Inquiry
IGFV-083 Recombinant Anti-CD3 x Anti-GD2 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD3 Mouse GD2 Mouse Inquiry
IGFV-037 Recombinant Anti-CD16 x Anti-GD2 Bispecific Antibody (IgG-scFv) Human IgG-scFv CD16 Mouse GD2 Mouse Inquiry
BSDB-153 Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Diabody) Human Diabody DTPA Mouse GD2 Mouse Inquiry
BSDB-138 Recombinant Anti-CEA x Anti-GD2 Bispecific Antibody (Diabody) Human Diabody CEA Mouse GD2 Mouse Inquiry
BSDB-126 Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (Diabody) Human Diabody CD64 Mouse GD2 Mouse Inquiry
BSDB-083 Recombinant Anti-CD3 x Anti-GD2 Bispecific Antibody (Diabody) Human Diabody CD3 Mouse GD2 Mouse Inquiry
BSDB-037 Recombinant Anti-CD16 x Anti-GD2 Bispecific Antibody (Diabody) Human Diabody CD16 Mouse GD2 Mouse Inquiry
BSFAB-153 Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Tandem Fab) Human Tandem Fab DTPA Mouse GD2 Mouse Inquiry
BSFAB-138 Recombinant Anti-CEA x Anti-GD2 Bispecific Antibody (Tandem Fab) Human Tandem Fab CEA Mouse GD2 Mouse Inquiry
BSFAB-126 Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD64 Mouse GD2 Mouse Inquiry
BSFAB-083 Recombinant Anti-CD3 x Anti-GD2 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD3 Mouse GD2 Mouse Inquiry
BSFAB-037 Recombinant Anti-CD16 x Anti-GD2 Bispecific Antibody (Tandem Fab) Human Tandem Fab CD16 Mouse GD2 Mouse Inquiry
BSFV-153 Recombinant Anti-DTPA x Anti-GD2 Bispecific Antibody (Tandem scFv) Human Tandem scFv DTPA Mouse GD2 Mouse Inquiry
BSFV-138 Recombinant Anti-CEA x Anti-GD2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CEA Mouse GD2 Mouse Inquiry
BSFV-126 Recombinant Anti-CD64 x Anti-GD2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD64 Mouse GD2 Mouse Inquiry
BSFV-083 Recombinant Anti-CD3 x Anti-GD2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD3 Mouse GD2 Mouse Inquiry
BSFV-037 Recombinant Anti-CD16 x Anti-GD2 Bispecific Antibody (Tandem scFv) Human Tandem scFv CD16 Mouse GD2 Mouse Inquiry

Background

GD2 is a disialoganglioside that is commonly found in cancers originating from neuroectodermal cells, such as human neuroblastoma and melanoma. However, in humans, GD2 is only present in the cerebellum and peripheral nerves. GD2 enhances tumor development by stimulating various processes such as the proliferation of tumor cells, mobility, emigration, attachment, and aggression. Therefore, disialoganglioside GD2 can be considered both a tumor-associated antigen and an appealing target for cancer treatment. Currently, there is ongoing development of monoclonal antibodies that specifically target GD2, as well as other treatments that aim to combat GD2. The most prevalent anti-GD2 monoclonal antibodies lyse tumor cells by complement-dependent cytotoxicity, induce necrosis and apoptosis through direct activation of cell death, and phagocytose and kill GD2-expressing tumor cells by ADCC. Additionally, anti-GD2 monoclonal antibodies have the potential to prevent cancer cells in circulation from homing in on and sticking to the extracellular matrix.

Fig.1 The cytotoxic effect of anti-GD2 and its impact on the neuroblastoma tumor microenvironment. (Chan and Carol, 2022) Fig.1 The cytotoxic effect of anti-GD2 and its impact on the neuroblastoma tumor microenvironment.1

Reference

  1. Chan, Godfrey Chi-Fung, and Carol Matias Chan. "Anti-GD2 directed immunotherapy for high-risk and metastatic neuroblastoma." Biomolecules 12.3 (2022): 358.
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