Recombinant Anti-VEGFR2 x Anti-VEGFR3 Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin) (BSFAB-SAR018)

Recombinant Anti-VEGFR2 x Anti-VEGFR3 Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin) is designed to be expressed as the α-Sarcin (SAR) fused to a tandem Fab recognizing VEGFR2 and VEGFR3. It contains three chains and a His-tag at the C/N terminus for affinity purification. The two Fd regions are connected by a flexible linker. This bispecific immunotoxin can deliver SAR to antigen-specific cells. Then SAR is a ribonuclease which can inhibit protein synthesis and kill the target cells. The bispecific immunotoxin is designed for the research of Cancers therapy.

Datasheet INQUIRY

Specifications

Targets

VEGFR2 & VEGFR3

Type

Bispecific Immunotoxin

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Cancers

Targets

Target 1

VEGFR2

Gene ID

3791

UniProt ID

A0A024RD88

Alternative Names

FLK1; CD309; VEGFR; VEGFR2; Vascular endothelial growth factor receptor 2; Kinase insert domain receptor; Fetal liver kinase 1; Kinase insert domain receptor, a type III receptor; KDR

Target 2

VEGFR3

Gene ID

2324

UniProt ID

P35916

Alternative Names

FLT4; PCL; FLT-4; FLT41; LMPH1A; VEGFR3; VEGFR-3; fms related tyrosine kinase 4; Vascular endothelial growth factor 3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-VEGFR2 x Anti-VEGFR3 Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin) (BSFAB-SAR018). Click the button below to contact us or submit your feedback about this product.

Recombinant Anti-VEGFR2 x Anti-VEGFR3 Tandem Fab-SAR immunotoxin (Bispecific Immunotoxin) (CAT#: BSFAB-SAR018)

Specifications

Targets

Customer Reviews and Q&As