It is likely that spontaneous tumor models will fill the important gap between simple in vivo tumor models and human clinical trials. As a world leader in the industry of animal models, Creative Biolabs can provide you the most innovative pre-clinical solutions for in vivo tumor modeling. Creative Biolabs' animal model platform offers numerous validated tumor models for your selection of cancer immunotherapeutics. Our laboratory animal workshop cultured various kinds of spontaneous mouse model including NHL, prostate carcinoma, lung carcinoma, head-and-neck carcinoma etc.
Spontaneous Mouse Models
Due to years of research on laboratory mouse, it's well known that some certain mouse strains are more liable to developing certain tumors. These strains of mice have high tumor incidence, particularly at an advanced age, providing another resource of mouse tumor models.
Spontaneous mouse models are experimental mice that develop tumors under ordinarily natural condition or that reserve to breed and cultivate due to the abnormal manifestation caused by genetic mutations. Spontaneous mouse models mainly focus on tumor and genetic diseases, including metabolic diseases, molecular disease and abnormal synthesis of specific proteins.
Advantages of Spontaneous Mouse Models in Creative Biolabs
Although plenty of xenograft or implanted tumor models have been widely used, the most effective way to discover the immunotherapeutic strategies is spontaneous models. These models are more relevant to the clinical settings, since spontaneous tumors develop in appropriate tissue circumstances and in a host conditioned by the physiological events of tumorigenesis and neoplastic progression while forming in the context of a viable immune system. Examples of such spontaneous models include NHL, prostate carcinoma, lung carcinoma, head-and-neck carcinoma, mammary carcinoma, melanoma, soft-tissue sarcoma and osteosarcoma.
Why choose us?
Spontaneous models refer to diseases that are analogous to human conditions that occur naturally in the animal being studied. These models are rare but informative. At Creative Biolabs, you have access to the largest collection of effective syngeneic mouse models in the world including not only the spontaneous models but also Syngeneic Cell Line Derived Tumor Models, Syngeneic Mice-derived Tumor Models, and Carcinogen-induced Mouse Models.
If you are interested in learning more about Creative Biolabs' animal models or drug discovery service, please contact us to get more information.
With extensive experience and excellent skills, scientists in Creative Biolabs is proud to offer other rodent tumor models as well as pharmacology studies for your scientific research:
For Research Use Only.
