Animal experiments have great contribution to our understanding of mechanisms of disease. The rodents are widely considered the model organism of choice for studying the diseases of humans, especially for mouse, with whom they share 99% of their genes. Rodent disease models can be subjected to biomedical experimentation not possible in patients. With years of experience and advanced technology, Creative Biolabs provides a breadth of quality non-genetically engineering models (NON-GEMs) to clients around the world. Our scientists are willing to assist you in selecting the most appropriate one for your research.
Non-Genetically Engineering Models (NON-GEMs)
Animal models are an essential tool to all areas of biomedical research. Animal models can provide results that allow us to deduce knowledge to study human diseases. Rodents, especially rats and mice, have been the prominent disease models used in biomedical research for well over a century, although other animals, such as non-human primates, zebrafish, fruit flies and roundworms, are also used. Mice and humans share most physiological and pathological features: similarities in nervous, cardiovascular, endocrine, immune, musculoskeletal and other internal organ systems have been extensively documented.
Rodents have been regarded as a reliable research species mainly due to their small size, abbreviated lifespan, reproductive affluence, known genetic background, as well as relative ease of procurement, handling, and housing. With the development of biotechnologies, various manipulations allow the establishment of rodent models accurately mimic the human disease model of interests, and accurately reflect the morphological and biochemical aspects of disease pathogenesis.
Due to the rich experience of rodent study, many methods, strategies, techniques, data, and reagent resources have been established. Non-genetically engineering models (NON-GEMs) has been applied to study various cancers, neurological disorders, heart diseases, hypertension, diabetes and so on. What's more, metabolic, physiological, behavioral stresses can be tested on mouse models, the results of which can be compared directly with human clinical information. Particularly, mice with various immunodeficiencies are significantly valuable for studying tumor growth and infectious diseases and can act as hosts to human tissues and cells.
Currently, Creative Biolabs offers a broad variety of well-established non-genetically engineering models (NON-GEMs) for our worldwide clients. With years of experience in the field of animal model and legendary professional skills, our scientists are willing to help you identify the most appropriate disease models for your research. Also, you can explore our extensive and broad-based library of rodent models to find the one you need.
Following is the list of available Non-Genetically engineering models (NON-GEMs) at Creative Biolabs, which are useful to explore human disease:
If you have any special needs in the establishment of rodent models or be interested in learning more about Creative Biolabs' animal models or drug discovery service, please contact us for more details.
For lab research use only.