Syngeneic cell lines derived tumor models are the most commonly examined models for preclinical exploration. With years of experience, Creative Biolabs has established scores of well-validated syngeneic tumor cell lines for various tumor types and validated them for preclinical in vivo use. Our models are absolutely verified and profiled, with checkpoint inhibitor benchmarking data available. Syngeneic models in Creative Biolabs includes nearly 20 cancer types, with over 30 models available or in development.
Syngeneic Cell Line Derived Tumor Models
Syngeneic models, also known as the mouse homograft tumors, have been regarded as a surrogate transplanted tumor platform (as opposite to human xenograft tumors) for in vivo pharmacological studies. And undoubtedly, syngeneic cell lines derived tumor models are the most commonly examined models for preclinical exploration.
Most checkpoint inhibitors were first confirmed by syngeneic cell line derived models as proof of concept (POC). Today, lots of syngeneic models have been extensively profiled genomically, immunologically and for I/O agent efficacy.
Advantages of Syngeneic Cell Line Derived Tumor Models:
Creative Biolabs offers a variety of effective syngeneic cell line derived models for your research on tumor drug discovery as shown in the following table:
Why choose us?
With rich experience in various cancer models and professional knowledge in murine solid tumors, Creative Biolabs will be your most ideal partner to support your research on oncology therapeutics. Our standard syngeneic models are used to interrogate novel immune treatments with a broad range of syngeneic cell lines available. We also provide bioluminescent models, allowing researchers to investigate clinically relevant metastatic invasion, metastatic lesions in secondary organs, and the evaluation of agents to target this metastasis. Our scientists can provide you an effective and accurate way to find the most appropriate model, particularly for your combination studies. If you are interested in learning more about Creative Biolabs' animal models or drug discovery service, please feel free to contact us for more details.
Moreover, in order to meet specific requirements and various research objectives of our customs, Creative Biolabs is proud to offer other common rodent tumor models which including but not limited to:
For Research Use Only.
