Syngeneic tumor models offer a helpful system for assessing novel single tumor agent and combination immunotherapies in animals with fully functional immunity. Creative Biolabs provides a set of syngeneic rodent models, including almost 20 types of cancer with over 30 types of models available or in development, as well as full immune cell profiling via FACS, RNAseq data, and treatment data available including a range of checkpoint inhibitors.
Cancer Immunotherapy
In recent years, cancer immunotherapy is becoming a principal focus in the field of oncology research. Therefore, oncology drugs which target the immune system are likely to be highly-anticipated. In fact, some researchers have predicted that by the year of 2023, almost half of the cancer treatments will be immunomodulatory, and the industry is reacting by developing new implements that can be employed in this fast-growing area.
Syngeneic Models
Cancer immunotherapies are aiming at cooperating with patients' immune systems to enhance native anti-tumor responses. Nowadays, with the success of new immunotherapy agents, syngeneic models have been regarded as reliable models for immunotherapy studies, after been shelved for decades. In the field of immunotherapy study, conventional xenograft models lack in relevance because of the animals' immunocompromised status.
Advantages of Syngeneic Models
Due to the capability of retaining intact immune system, syngeneic models could particularly apply to the studies of immunologically-based targeted therapies and provide an efficient way to explore how cancer therapies act in the presence of a functional immune system.
Our Services
Creative Biolabs offers a wide range of syngeneic tumor models in rodent armed with well-characterized responses to known immune checkpoint inhibitors such as anti-CTLA-4, anti-PDL-1, and anti-PD-1. With rich experience in various cancer models and professional knowledge in murine solid tumors, Creative Biolabs will be your most ideal partner to support your research on oncology therapeutics.
We are able to establish a variety of cancer models according to your demand and investigate all immunological and related biomarkers as well as all cancer-related parameters.
In addition, scientists in Creative Biolabs spare no effort to establish other rodent tumor models for our worldwide clients:
If you are interested in learning more about Creative Biolabs' animal models or drug discovery service, please contact us to get more detailed information.
For Research Use Only.
