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CAR IVT mRNA Products

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

CAR IVT mRNA in Cancer Immunotherapy

Viral delivery vector-mediated transfection could cause insertional mutagenesis that limits their applications in cancer immunotherapy. Due to the safety and facile production, in vitro-transcribed (IVT)-mRNA is an alternative for transient expression of chimeric antigen receptors (CARs) in human T cells and NK cells. Based on our proprietary production platform, Creative Biolabs is committed to offering high-quality CAR IVT products covering plasmid, mRNA, and LNP products.

IVT mRNA application in adoptive cell therapy. (Foster, et al., 2019)Fig.1 IVT mRNA application.1

CAR IVT mRNA Products

Creative Biolabs is committed to improving our products and services to meet the growing requirements. Our team is experienced in IVT process development and help accelerate your project significantly. We provide a full range of CAR IVT mRNA products for the development of CAR-based therapeutics. Our mRNA products go through a series of rigorous quality control assays to ensure high quality.

CAR IVT mRNA Service

Creative Biolabs offers CAR IVT mRNA products and services to suit your needs. CAR IVT mRNAs can be custom-made to meet your specific requirements. A dedicated team of experts with years of experience will be assigned to your project for guidance and support. Our IVT mRNA services are flexible and can be customized according to your requirements. You can provide the cDNA your lab has at hand or the sequence of the gene of interest. Our team will be able to help you with mRNA manufacturing through the process of transcription so that you can focus on the discovery and innovation.

Our experts help design your IVT mRNA if desired. The project can start from various sources:

  • Your own cDNA
  • Your own sequence design
  • Sequences that are optimized and synthesized by Creative Biolabs

Please contact us to discuss your specific CAR IVT mRNA manufacturing needs.

Workflow

Workflow of IVT mRNA manufacture. (Creative Biolabs Original)Fig.2 Workflow of IVT mRNA manufacture. (Creative Biolabs)

Reference

  1. Foster, J.B.; et al. The emerging role of in vitro-transcribed mRNA in adoptive T cell immunotherapy. Molecular Therapy. 2019, 27(4): 747-56.
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