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Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (Diabody)  (BSDB-068)

Recombinant Anti-CD3 x Anti-CD44 Bispecific Antibody (Diabody) is designed to be expressed as two polypeptide chains respectively. The two chains are cross-over pairing to form a dimer. It contains a His-tag for affinity purification. This BsAb can retarget T cells to tumor cells. It is designed for the research of Glioblastoma; Squamous cancer therapy.

Specifications

Targets
CD3 & CD44
Type
Diabody
Species Reactivity
Human
Target 1
CD3
Host Animal 1
Mouse
Target 2
CD44
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Glioblastoma; Squamous cancer

Targets

Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
CD44
Gene ID
UniProt ID
Alternative Names
CD44; CD44 antigen; ECMRIII; Extracellular matrix receptor III; HCAM; Homing cell adhesion molecule; Pgp-1; phagocytic glycoprotein-1; HUTCH-1; Ly-24; Pgp-1; HERMES; AU023126; AW121933; AW146109

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