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Recombinant Human Anti-CD3 x Human Anti-FAP Bispecific Antibody (Fab-Fv)  (CAT#: FABFV-H256)

Recombinant Anti-CD3 x Anti-FAP Bispecific Antibody (Fab-Fv) is designed to be expressed as two polypeptide chains. The heavy chain Fd fragment and light chain of an anti-CD3 antibody are fused with the VL and VH domains of an anti-FAP antibody respectively. It can form natural in vivo heterodimerization. This BsAb can retarget T cells to tumor cells. It is designed for the research of Epithelial cancers therapy.
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Specifications

Targets
CD3 & FAP
Type
Fab-Fv
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Epithelial cancers

Targets

Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
FAP
Gene ID
UniProt ID
Alternative Names
FAP; fibroblast activation protein, alpha; FAPA; SIMP; Fibroblast activation protein; DPPIV; prolyl endopeptidase FAP; seprase; FAPalpha; dipeptidyl peptidase FAP; surface-expressed protease; post-proline cleaving enzyme; gelatine degradation protease FAP; F19 cell surface antigen; integral membrane serine protease; serine integral membrane protease; 170 kDa melanoma membrane-bound gelatinase
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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