Recombinant Anti-CD64 x Anti-EGFR Bispecific Antibody (Bibody)  (BIBD-125)

Recombinant Anti-CD64 x Anti-EGFR Bispecific Antibody (Bibody) is a Fab-scFv format that uses heterodimeric Fab as a scaffold, and a scFv region linked to one of its heavy (Fd) or light (L) chain. The scFv of the anti-CD64 specificity is fused to the anti-CD64 heavy or light chain of the Fab. This BsAb can retarget neutrophils cells to tumor cells. It is designed for the research of Head and neck cancer; Colorectal cancer (CRC); Glioblastoma multiforme (GBM); Squamous cancer; Glioblastoma; Medulloblastoma; Non-small cell lung cancer (NSCLC); Renal cell cancer (RCC); Solid tumors therapy.

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