Home > Products > CD64 & EGFR > Recombinant Human Anti-CD64 x Human Anti-EGFR Bispecific Antibody (scIgG)

Recombinant Human Anti-CD64 x Human Anti-EGFR Bispecific Antibody (scIgG)  (CAT#: SCIGG-H299)

Recombinant Anti-CD64 x Anti-EGFR Bispecific Antibody (scIgG) is designed to be expressed as two chains, each chain has the same units with their parental IgG antibodies, anti-CD64 and anti-EGFR IgGs. The two chains form heterodimer via Fc KIH technology. This BsAb can retarget neutrophils cells to tumor cells. It is designed for the research of Head and neck cancer; Colorectal cancer (CRC); Glioblastoma multiforme (GBM); Squamous cancer; Glioblastoma; Medulloblastoma; Non-small cell lung cancer (NSCLC); Renal cell cancer (RCC); Solid tumors therapy.
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Specifications

Targets
CD64 & EGFR
Type
Single chain IgGs
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Head and neck cancer; Colorectal cancer (CRC); Glioblastoma multiforme (GBM); Squamous cancer; Glioblastoma; Medulloblastoma; Non-small cell lung cancer (NSCLC); Renal cell cancer (RCC); Solid tumors
Host Animal 1
Human
Host Animal 2
Human

Targets

Target 1
CD64
Gene ID
2209
UniProt ID
P12314
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI
Target 2
EGFR
Gene ID
1956
UniProt ID
P00533
Alternative Names
EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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