Home > Products > CD64 & malaria antigen > Recombinant Human Anti-CD64 x Human Anti-malaria antigen Bispecific Antibody (IgG(L)-scFv)

Recombinant Human Anti-CD64 x Human Anti-malaria antigen Bispecific Antibody (IgG(L)-scFv)  (IGLFV-H303)

Recombinant Anti-CD64 x Anti-malaria antigen Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-CD64 antibody are fused to the C terminus of an anti-malaria antigen IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can retarget NK cells to genus plasmodium. It is designed for the research of Malaria therapy.

Specifications
Targets
CD64 & malaria antigen
Type
Appended IgGs
Species Reactivity
Human
Target 1
CD64
Host Animal 1
Human
Target 2
malaria antigen
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Malaria
Targets
Target 1
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI
Target 2
malaria antigen
Alternative Names
malaria antigen; parasitic protozoans
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