Recombinant Anti-CD64 x Anti-malaria antigen Bispecific Antibody (IgG-scFv) (IGFV-129)

Recombinant Anti-CD64 x Anti-malaria antigen Bispecific Antibody (IgG-scFv) is designed to be expressed as a LC and an extended HC with scFv moiety linked to the C terminus. It is a symmetric bispecific and tetravalent molecule, bivalent for each antigen specificity, 2+2 antigen-binding valency. This BsAb can retarget NK cells to genus plasmodium. It is designed for the research of Malaria therapy.

Datasheet

Specifications

Targets

CD64 & malaria antigen

Type

IgG-scFv

Species Reactivity

Human

Target 1

CD64

Host Animal 1

Mouse

Target 2

malaria antigen

Host Animal 2

Mouse

Application

FuncS; Promising therapeutic agent

Related Disease

Malaria

Targets

Target 1

CD64

Gene ID

2209

UniProt ID

P12314

Alternative Names

FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

Target 2

malaria antigen

Alternative Names

malaria antigen; parasitic protozoans

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