Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Fab-IgG) (FABIG-145)

Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can bind two factors simultaneously. It is designed for the research of Renal cell cancer (RCC) therapy.

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Specifications

Targets

CTLA4 & GLUT2

Type

Fab-IgG

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Renal cell cancer (RCC)

Targets

Target 1

CTLA4

Gene ID

1493

UniProt ID

P16410

Alternative Names

CTLA4; cytotoxic T-lymphocyte-associated protein 4; CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3; cytotoxic T-lymphocyte protein 4; CD152 isoform; celiac disease 3; insulin-dependent diabetes mellitus 12; cytotoxic T-lymphocyte-associated serine esterase-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4

Target 2

GLUT2

Gene ID

6514

UniProt ID

P11168

Alternative Names

SLC2A2; solute carrier family 2 (facilitated glucose transporter), member 2; GLUT2; solute carrier family 2, facilitated glucose transporter member 2; glucose transporter type 2, liver

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (Fab-IgG) (CAT#: FABIG-145)

Specifications

Targets

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