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Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (scFv-CH3)  (CAT#: BSFC-145)

Recombinant Anti-CTLA4 x Anti-GLUT2 Bispecific Antibody (scFv-CH3) contains two chains. The anti-CTLA4 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-GLUT2 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can bind two factors simultaneously. It is designed for the research of Renal cell cancer (RCC) therapy.
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Specifications

Targets
CTLA4 & GLUT2
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Renal cell cancer (RCC)

Targets

Target 1
CTLA4
Gene ID
UniProt ID
Alternative Names
CTLA4; cytotoxic T-lymphocyte-associated protein 4; CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3; cytotoxic T-lymphocyte protein 4; CD152 isoform; celiac disease 3; insulin-dependent diabetes mellitus 12; cytotoxic T-lymphocyte-associated serine esterase-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
Target 2
GLUT2
Gene ID
UniProt ID
Alternative Names
SLC2A2; solute carrier family 2 (facilitated glucose transporter), member 2; GLUT2; solute carrier family 2, facilitated glucose transporter member 2; glucose transporter type 2, liver
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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