Recombinant Anti-DR5 x Anti-FAP Bispecific Antibody (Fv-IgG)  (BSDG-152)

Recombinant Anti-DR5 x Anti-FAP Bispecific Antibody (Fv-IgG) is an appended IgG format, which has 2+2 antigen-binding valency. This dual variable domain IgG is generated by appending variable domains of an anti-DR5 IgG with similar domains from an anti-FAP antibody via short peptide linkers, or vice versa. This BsAb can induce targeted apoptosis by activation of the death receptor. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.

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