Name: Recombinant Anti-DR5 x Anti-FAP Bispecific Antibody (Fv-IgG)
SKU: BSDG-152
Rating: 5 (1 reviews)

Recombinant Anti-DR5 x Anti-FAP Bispecific Antibody (Fv-IgG) is an appended IgG format, which has 2+2 antigen-binding valency. This dual variable domain IgG is generated by appending variable domains of an anti-DR5 IgG with similar domains from an anti-FAP antibody via short peptide linkers, or vice versa. This BsAb can induce targeted apoptosis by activation of the death receptor. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.

Datasheet INQUIRY

Specifications

Targets

DR5 & FAP

Type

Fv-IgG

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Breast cancer; Ovary cancer; Colon cancer; Lung cancer

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

DR5

Gene ID

8795

UniProt ID

O14763

Alternative Names

DR5; Death Receptor 5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5; Tumor necrosis factor receptor superfamily member 10B; TNFRSF10B

Target 2

FAP

Gene ID

2191

UniProt ID

B4DLR2

Alternative Names

FAP; fibroblast activation protein, alpha; FAPA; SIMP; Fibroblast activation protein; DPPIV; prolyl endopeptidase FAP; seprase; FAPalpha; dipeptidyl peptidase FAP; surface-expressed protease; post-proline cleaving enzyme; gelatine degradation protease FAP; F19 cell surface antigen; integral membrane serine protease; serine integral membrane protease; 170 kDa melanoma membrane-bound gelatinase

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-DR5 x Anti-FAP Bispecific Antibody (Fv-IgG) (CAT#: BSDG-152)

Specifications

Targets

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