Home > Products > DR5 & FAP > Recombinant Human Anti-DR5 x Human Anti-FAP Bispecific Antibody (scIgG)

Recombinant Human Anti-DR5 x Human Anti-FAP Bispecific Antibody (scIgG)  (SCIGG-H320)

Recombinant Anti-DR5 x Anti-FAP Bispecific Antibody (scIgG) is designed to be expressed as two chains, each chain has the same units with their parental IgG antibodies, anti-DR5 and anti-FAP IgGs. The two chains form heterodimer via Fc KIH technology. This BsAb can induce targeted apoptosis by activation of the death receptor. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.

Specifications
Targets
DR5 & FAP
Type
Single chain IgGs
Species Reactivity
Human
Target 1
DR5
Host Animal 1
Human
Target 2
FAP
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Breast cancer; Ovary cancer; Colon cancer; Lung cancer
Targets
Target 1
DR5
Gene ID
UniProt ID
Alternative Names
DR5; Death Receptor 5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5; Tumor necrosis factor receptor superfamily member 10B; TNFRSF10B
Target 2
FAP
Gene ID
UniProt ID
Alternative Names
FAP; fibroblast activation protein, alpha; FAPA; SIMP; Fibroblast activation protein; DPPIV; prolyl endopeptidase FAP; seprase; FAPalpha; dipeptidyl peptidase FAP; surface-expressed protease; post-proline cleaving enzyme; gelatine degradation protease FAP; F19 cell surface antigen; integral membrane serine protease; serine integral membrane protease; 170 kDa melanoma membrane-bound gelatinase
Our services and products are only for lab research, not for any diagnostic or therapeutic use.

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