Anti-A1CF Aptamer SELEX Service(Cat#: CTApt-1196)

This is an aptamer development services to screening aptamers binds to the A1CF with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target A1CF
Alternative Names APOBEC1 Complementation Factor; ACF; ASP; APOBEC1CF; ACF64; ACF65; Apobec-1 Complementation Factor (ACF) (ASP) ; APOBEC-1 Stimulating Protei; APOBEC1-Stimulating Protein; Apo-B RNA Editing Protein; A1CF
Gene ID 29974
UniProt ID Q9NQ94
Target Overview Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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