Anti-A1CF Aptamer(Cat#: CTApt-1196)
This product is an aptamer which binds to the A1CF with an affinity of 1nM~1μM.
Specific Inquiry 
Summary
Specifications
| Target Category |
Protein |
| Target |
A1CF |
| Alternative Names |
APOBEC1 Complementation Factor; ACF; ASP; APOBEC1CF; ACF64; ACF65; Apobec-1 Complementation Factor (ACF) (ASP) ; APOBEC-1 Stimulating Protei; APOBEC1-Stimulating Protein; Apo-B RNA Editing Protein; A1CF |
| Gene ID |
29974 |
| UniProt ID |
Q9NQ94 |
| Target Overview |
Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene. |
| Chemical Modification |
DNA/RNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
