Complement System Knowledge Center

• Complement System Knowledge Center
  • Complement System Composition
• Research Highlights
  • Activation of the Complement System by Urban Particulate Matter
  • Adipsin Is a Potential Predictor for Preeclampsia in Early Pregnancy
  • Alternative C3 Complement System: Lipids and Atherosclerosis
  • Antimicrobial Peptide as Complement System Modulator
  • ARGX-117, a therapeutic complement inhibiting antibody targeting C2
  • Autoantibodies Against the Complement Regulator Factor H in the Serum of Patients
  • C4b Binding Protein Acts as an Innate Immune Effector Against Influenza A Virus
  • Cerebrospinal fluid complement system biomarkers in demyelinating disease
  • Coagulation Complement Activation and Cerebral Hypoperfusion
  • Complement Activation in the Central Nervous System
  • Complement Activation in the Disease Course of Coronavirus Disease 2019
  • Complement Pathway Activation Is Associated With COVID-19 Mortality
  • Complement as the enabler of carfilzomib-induced thrombotic microangiopathy
  • Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Subjects
  • Complement component C4 levels in the cerebrospinal fluid and plasma of patients
  • Complement DAF is a modulator of influenza A virus lung immunopathology
  • Complement Regulation in Human Tenocytes under the Influence of Anaphylatoxin C5a
  • Danicopan an oral CFD inhibitor for paroxysmal nocturnal hemoglobinuria
  • Dendrimer end-terminal motif-dependent evasion of complement activation
  • Endothelial C3a receptor mediates vascular inflammation and BBB permeability
  • Gamma subunit of complement component 8 is a neuroinflammation inhibitor
  • Genetic and molecular evidence for complement dysregulation in patients
  • Inhibition of complement C5a receptor protects lung cells and tissues
  • Interference of the Zika Virus E-Protein With the MAC of the Complement System
  • Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins
  • Microglial trogocytosis and the complement system regulate axonal pruning in vivo
  • Modulation of complement activation by pentraxin-3 in prostate cancer
  • Monitoring of the Complement System Status in Patients
  • Monoclonal Antibodies Capable of Inhibiting Complement Downstream of C5
  • Overexpression of C4A promotes excessive synaptic loss and behavioral changes
  • Quantitative multiplex profiling of the complement system to diagnose diseases
  • REV-ERBα mediates complement expression and diurnal regulation of phagocytosis
  • SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation
  • Specific Evolution and Gene Family Expansion of C3 and Regulatory CFH in Fish
  • Syk facilitates phagosome-lysosome fusion by regulating actin-remodeling
  • Synaptic and complement markers in extracellular vesicles in multiple sclerosis
  • The allosteric modulation of complement C5 by knob domain peptides
  • The complement system drives local inflammatory tissue priming
  • The solution structure of the complement deregulator FHR5 reveals a compact dimer
  • Two human antibodies enhance binding of CFH by stabilizing the CFH binding site
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