Anti-A2ML1 Aptamer SELEX Service(Cat#: CTApt-1329)

This is an aptamer development services to screening aptamers binds to the A2ML1 with an affinity of 1nM~1μM.

Datasheet MSDS COA
Specific Inquiry 
Size
5’ Modification
 
3’ Modification
 
Add To
Online Inquiry

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number

TOP
Summary

Specifications
Target Category Protein
Target A2ML1
Alternative Names Alpha-2-Macroglobulin Like 1; C3 And PZP-Like, Alpha-2-Macroglobulin Domain Containing 9; Alpha-2-Macroglobulin-Like Protein 1; CPAMD9; P170; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 9; FLJ25179; A2ML1; OMS
Gene ID 144568
UniProt ID A8K2U0
Target Overview This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS; PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
Online Inquiry
×