Anti-ABCA1 Aptamer SELEX Service(Cat#: CTApt-891)
This is an aptamer development services to screening aptamers binds to the ABCA1 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ABCA1 |
| Alternative Names |
ATP Binding Cassette Subfamily A Member 1; ATP-Binding Cassette, Sub-Family A (ABC1), Member 1; ATP-Binding Cassette Sub-Family A Member 1; Phospholipid-Transporting ATPase ABCA1; Cholesterol Efflux Regulatory Protein; ABC-1; ABC1; CERP; TGD; ATP-Binding Cassette Transporter A1; ATP-Binding Cassette Transporter 1; ATP-Binding Cassette 1; Tangier Disease; Membrane-Bound; EC 3.6.3.41; EC 2.8.1.8; EC 2.7.7.8; EC 7.6.2.1; HDLCQTL13; EC 3.6.3; HDLDT1; HPALP1; ABCA1 |
| Gene ID |
19 |
| UniProt ID |
O95477 |
| Target Overview |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
