Anti-ABCA7 Aptamer SELEX Service(Cat#: CTApt-2484)

This is an aptamer development services to screening aptamers binds to the ABCA7 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ABCA7
Alternative Names ATP Binding Cassette Subfamily A Member 7; ATP-Binding Cassette, Sub-Family A (ABC1), Member 7; ATP-Binding Cassette Sub-Family A Member 7; Phospholipid-Transporting ATPase ABCA7; Macrophage ABC Transporter; Autoantigen SS-N; ABCA-SSN; ABCX; ABCA7; AD9
Gene ID 10347
UniProt ID Q8IZY2
Target Overview The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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