This is an aptamer development services to screening aptamers binds to the ABCC6 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ABCC6 |
| Alternative Names | ATP Binding Cassette Subfamily C Member 6; MRP6; ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 6; Anthracycline Resistance-Associated Protein; Multi-Specific Organic Anion Transporter E; Multidrug Resistance-Associated Protein 6; EST349056; MOAT-E; MLP1; URG7; ARA; ATP-Binding Cassette Sub-Family C Member 6; Pseudoxanthoma Elasticum; URG7 Protein; ABC34; GACI2; MOATE; ABCC6; PXE1; PXE |
| Gene ID | 368 |
| UniProt ID | O95255 |
| Target Overview | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |