This is an aptamer development services to screening aptamers binds to the ACOT11 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ACOT11 |
| Alternative Names | Acyl-CoA Thioesterase 11; BFIT; StAR-Related Lipid Transfer (START) Domain Containing 14; Palmitoyl-Coenzyme A Thioesterase; Thioesterase, Adipose Associated; Brown Fat-Inducible Thioesterase; Acyl-Coenzyme A Thioesterase 11; Acyl-CoA Thioester Hydrolase 11; Adipose-Associated Thioesterase; KIAA0707; STARD14; THEM1; THEA; Thioesterase Superfamily Member 1; START Domain Containing 14; EC 3.1.2.1; EC 3.1.2.- ; EC 3.1.2.2; ACOT11; BFIT1 |
| Gene ID | 26027 |
| UniProt ID | Q8WXI4 |
| Target Overview | This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |